03083cam a22002298b 4500003000500000005001700005008004100022020001800063040001400081082001600095100003200111245010800143260003900251300007400290504005100364505215000415650004802565650003302613942006202646999001902708952012602727322820231025110929.02023  s2023    nyua     b    001 0 eng    a9780816066810  ardac322800a660.65 HODG1 aHodge, Russ,d1961-918342810aGenetic engineering :bmanipulating the mechanisms of life /cRuss Hodge ; foreword by Nadia Rosenthal.  aNew York :bFacts On File,cc2009.  axx, 219 pages :billustration (some col.), col. map, ports. ;c24 cm.  aIncludes bibliographical references and index.0 aFrom breeding to a science of heredity -- The origins of domestic plants and animals -- The rise of agriculture and domestication -- Early ideas of inheritance -- The girl who gave birth to rabbits -- Heredity and the theory of evolution -- Gregor mendel discovers the laws of heredity -- Classical genetics (1900-1950) -- Cell theory and the discovery of chromosomes -- The rediscovery of mendel's work -- The debate over natural selection -- Chromosomes and heredity -- Sex and the X-Y chromosomes -- Fruit flies and the birth of the modern laboratory -- Gene maps -- Chromosome puzzles -- Maize and "jumping genes" -- "One gene makes one enzyme" -- Molecular genetics: what genes are and how they work (1950-1970) -- Physics stimulates new ways of thinking about genes -- Genes are made of DNA -- The double helix -- RNA is the messenger -- The architecture of genes -- On-off switches for genes -- The flow of information from gene to protein in complex organisms -- The rise of genetic engineering (1970-1990) -- Recombinant DNA -- "Natural" genetic engineering -- Molecular cloning and using bacteria as drug factories -- DNA sequencing -- The polymerase chain reaction (PCR) -- Making and marketing genetically modified plants and animals for food -- Knock outs, knock ins, and other methods to study gene functions -- Beatrice Mintz: a pioneer of mouse genetics -- Transgenic animals and models of human disease -- DNA fingerprinting -- Genetic engineering in the age of genomes -- The complexity of genomes -- Introns and alternative splicing -- Non-coding RNAs -- Quality control: how cells detect defective genes -- RNA knock outs -- Molecular machines -- Conditional mutagenesis -- Other methods of controlling the output of genes -- Molecular medicine and gene therapies -- Personalized medicine in the genome age -- DNA vaccines and t cell therapies -- Ethics and genetic engineering -- Reproductive cloning -- Therapeutic cloning and experiments with human cells -- Genetic testing and concerns about eugenics -- GM foods and the rise of environmental movements -- Owning genes, genomes, and living beings -- A look farther ahead. 0aGenetic engineeringvPopular works.9183429 0aMolecular machinery.9183430  2ddccBOOKw169xBoniswa Ngcongoloy169zBoniswa Ngcongolo  c759365d759364  00102ddc40708600aERMELbKHULLcNon_Fictiond2023-10-25l0o660.65 HODGp33228031000221r2023-10-25w2023-10-25yBOOK