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082	0	0	_a660.65 HODG
100	1		_aHodge, Russ, _d1961- _9183428
245	1	0	_aGenetic engineering : _bmanipulating the mechanisms of life / _cRuss Hodge ; foreword by Nadia Rosenthal.
260			_aNew York : _bFacts On File, _cc2009.
300			_axx, 219 pages : _billustration (some col.), col. map, ports. ; _c24 cm.
504			_aIncludes bibliographical references and index.
505	0		_aFrom breeding to a science of heredity -- The origins of domestic plants and animals -- The rise of agriculture and domestication -- Early ideas of inheritance -- The girl who gave birth to rabbits -- Heredity and the theory of evolution -- Gregor mendel discovers the laws of heredity -- Classical genetics (1900-1950) -- Cell theory and the discovery of chromosomes -- The rediscovery of mendel's work -- The debate over natural selection -- Chromosomes and heredity -- Sex and the X-Y chromosomes -- Fruit flies and the birth of the modern laboratory -- Gene maps -- Chromosome puzzles -- Maize and "jumping genes" -- "One gene makes one enzyme" -- Molecular genetics: what genes are and how they work (1950-1970) -- Physics stimulates new ways of thinking about genes -- Genes are made of DNA -- The double helix -- RNA is the messenger -- The architecture of genes -- On-off switches for genes -- The flow of information from gene to protein in complex organisms -- The rise of genetic engineering (1970-1990) -- Recombinant DNA -- "Natural" genetic engineering -- Molecular cloning and using bacteria as drug factories -- DNA sequencing -- The polymerase chain reaction (PCR) -- Making and marketing genetically modified plants and animals for food -- Knock outs, knock ins, and other methods to study gene functions -- Beatrice Mintz: a pioneer of mouse genetics -- Transgenic animals and models of human disease -- DNA fingerprinting -- Genetic engineering in the age of genomes -- The complexity of genomes -- Introns and alternative splicing -- Non-coding RNAs -- Quality control: how cells detect defective genes -- RNA knock outs -- Molecular machines -- Conditional mutagenesis -- Other methods of controlling the output of genes -- Molecular medicine and gene therapies -- Personalized medicine in the genome age -- DNA vaccines and t cell therapies -- Ethics and genetic engineering -- Reproductive cloning -- Therapeutic cloning and experiments with human cells -- Genetic testing and concerns about eugenics -- GM foods and the rise of environmental movements -- Owning genes, genomes, and living beings -- A look farther ahead.
650		0	_aGenetic engineering _vPopular works. _9183429
650		0	_aMolecular machinery. _9183430
942			_2ddc _cBOOK _w169 _xBoniswa Ngcongolo _y169 _zBoniswa Ngcongolo
999			_c759365 _d759364